Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565755 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL17089961 | 0.90 | CRHR1 (0.44) | ALDH1A1LMNASMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL13564937 | 0.89 | POLB (0.41) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL17090296 | 0.89 | POLB (0.41) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL17090355 | 0.87 | CRHR1 (0.42) | ALDH1A1LMNASMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL13565190 | 0.87 | CRHR1 (0.42) | ALDH1A1LMNASMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL13438760 | 0.86 | CRHR1 (0.46) | CYP3A4CRHR1L3MBTL1 | |
| SCHEMBL11934886 | 0.86 | CRHR1 (0.46) | CYP3A4CRHR1L3MBTL1 | |
| SCHEMBL17090128 | 0.86 | MEN1 (0.43) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL13565746 | 0.86 | MEN1 (0.43) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |