Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565452 | 1.00 | DRD2 (0.39) | DRD2HTR2ADRD3CNR2ALDH1A1 | |
| SCHEMBL13565810 | 0.86 | MEN1 (0.43) | CNR2ALDH1A1 | |
| SCHEMBL13565122 | 0.86 | MEN1 (0.43) | CNR2ALDH1A1 | |
| SCHEMBL11934893 | 0.81 | TRPM5 (0.40) | DRD2HTR2ADRD3CNR2ALDH1A1 | |
| SCHEMBL17089966 | 0.81 | TRPM5 (0.40) | DRD2HTR2ADRD3CNR2ALDH1A1 | |
| SCHEMBL10114644 | 0.80 | NPY5R (0.48) | ALDH1A1 | |
| SCHEMBL13204259 | 0.80 | NPY5R (0.48) | ALDH1A1 | |
| SCHEMBL17090112 | 0.79 | MAOB (0.43) | ALDH1A1 | |
| SCHEMBL11935262 | 0.79 | MAOB (0.43) | ALDH1A1 | |
| SCHEMBL11936277 | 0.79 | LMNA (0.40) | DRD2HTR2ADRD3CNR2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |