Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090503 | 0.88 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL17090504 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KMT2AL3MBTL1MEN1MAPT | |
| SCHEMBL17090474 | 0.84 | LMNA (0.46) | ALDH1A1L3MBTL1MAPTLMNAGAA | |
| SCHEMBL13564994 | 0.84 | LMNA (0.46) | ALDH1A1L3MBTL1MAPTLMNAGAA | |
| SCHEMBL11936027 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KMT2AL3MBTL1MEN1MAPT | |
| SCHEMBL10116393 | 0.80 | RAB9A (0.67) | ALDH1A1KMT2AL3MBTL1MEN1MAPT | |
| SCHEMBL13566048 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL17090096 | 0.79 | HTR2B (0.39) | ALDH1A1MAPT | |
| SCHEMBL11935683 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2AL3MBTL1MEN1MAPT | |
| SCHEMBL13565590 | 0.76 | CTPS1 (0.45) | ALDH1A1MAPTLMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |