Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DDIT3 | P35638 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564994 | 1.00 | LMNA (0.46) | LMNATDP1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL17090551 | 0.89 | DDIT3 (0.49) | LMNAALDH1A1SMN1; SMN2GAARXFP1 | |
| SCHEMBL13565262 | 0.89 | DDIT3 (0.49) | LMNAALDH1A1SMN1; SMN2GAARXFP1 | |
| SCHEMBL17090098 | 0.86 | LMNA (0.46) | LMNATDP1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL13566055 | 0.85 | TDP1 (0.50) | LMNATDP1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11940095 | 0.84 | GHSR (0.40) | LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11935854 | 0.84 | GHSR (0.40) | LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17090486 | 0.84 | ALDH1A1 (0.52) | LMNAALDH1A1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL10116233 | 0.82 | RXFP1 (0.66) | LMNAALDH1A1SMN1; SMN2TP53GAA | |
| SCHEMBL10134521 | 0.82 | RXFP1 (0.66) | LMNAALDH1A1SMN1; SMN2TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |