Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14418436 | 0.83 | HTT (0.51) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL10114282 | 0.83 | HTT (0.51) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL13565755 | 0.79 | ALDH1A1 (0.50) | CRHR1ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL17089949 | 0.79 | ALDH1A1 (0.50) | CRHR1ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL17089961 | 0.76 | CRHR1 (0.44) | CRHR1ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL13105500 | 0.76 | SMYD3 (0.43) | CRHR1ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL11935207 | 0.76 | SMYD3 (0.43) | CRHR1ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL13438895 | 0.76 | SMYD3 (0.43) | CRHR1ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL17090253 | 0.74 | NPC1 (0.38) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL13565752 | 0.74 | NPC1 (0.38) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |