Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.44 |
| ▸ | DRD3 | P35462 | 7/20 | 0.40 |
| ▸ | DRD1 | P21728 | 6/20 | 0.40 |
| ▸ | DRD4 | P21917 | 6/20 | 0.40 |
| ▸ | DRD5 | P21918 | 6/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15486943 | 0.77 | DRD2 (0.38) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL7030007 | 0.75 | DRD2 (0.41) | DRD2DRD3HTR1D | |
| SCHEMBL1709095 | 0.71 | HSD17B10 (0.35) | DRD2DRD1 | |
| SCHEMBL24308956 | 0.69 | ALDH1A1 (0.47) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL9007737 | 0.68 | DRD2 (0.48) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL1282300 | 0.67 | DRD1 (0.39) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL23336944 | 0.67 | DRD2 (0.38) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL12533492 | 0.67 | DRD2 (0.38) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL19599368 | 0.67 | DRD2 (0.47) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL15478973 | 0.67 | DRD2 (0.33) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691992-B2 | Octahydro biquinoline compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-04-08 | — | — | US | disclosed |
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | CYP2S1, HCRTR2, CYP2B6 | DRD2 225/4885DRD3 443/4885DRD1 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.