Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.57 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709219 | 0.86 | SCN9A (0.74) | SCN9AKMT2AMEN1KDM4EPOLB | |
| SCHEMBL1286845 | 0.80 | SCN9A (0.66) | SCN9AKMT2APOLBLMNAALDH1A1 | |
| SCHEMBL1709222 | 0.80 | SCN9A (0.60) | SCN9AKMT2APOLBLMNAALDH1A1 | |
| SCHEMBL10072036 | 0.79 | SCN9A (0.55) | SCN9AKMT2AMEN1MAPTKDM4E | |
| SCHEMBL10072166 | 0.78 | SCN9A (0.60) | SCN9AKMT2ADRD2DRD3ALDH1A1 | |
| SCHEMBL10072037 | 0.78 | SCN9A (0.62) | SCN9AKMT2AABCG2MAPTPOLB | |
| SCHEMBL10072168 | 0.77 | SCN9A (0.56) | SCN9AKMT2AMEN1MAPTKDM4E | |
| SCHEMBL10072167 | 0.77 | SCN9A (0.61) | SCN9AKMT2APOLBALDH1A1 | |
| SCHEMBL1709220 | 0.74 | SCN9A (0.55) | SCN9AKMT2A | |
| SCHEMBL1709207 | 0.74 | SCN9A (0.54) | SCN9AKMT2APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047703-A2 | CYCLOPROPYL-SPIRO-PIPERIDINES USEFUL AS SODIUM CHANNEL BLOCKERS | SCHERING CORPORATION (US) | 2012-04-12 | — | — | WO | disclosed |