Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18522488 | 0.77 | MAPK1 (0.43) | MAPK1GRNSORT1 | |
| SCHEMBL8032315 | 0.77 | MAPK1 (0.43) | MAPK1GRNSORT1 | |
| SCHEMBL1703529 | 0.77 | MAPK1 (0.43) | MAPK1GRNSORT1 | |
| SCHEMBL15925085 | 0.75 | MAPK1 (0.41) | MAPK1GRNSORT1 | |
| SCHEMBL1709291 | 0.75 | MAPK1 (0.41) | MAPK1GRNSORT1 | |
| SCHEMBL8380546 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL8380494 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL1709281 | 0.72 | CYP2D6 (0.42) | — | |
| SCHEMBL14374875 | 0.71 | MAPK1 (0.38) | MAPK1GRNSORT1 | |
| SCHEMBL1709302 | 0.70 | MMP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PLOD3, COL1A1, THPO | MAPK1 2497/4885GRN 3021/4885SORT1 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.