Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29196210 | 0.88 | HPGD (0.70) | HPGDHSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL179082 | 0.88 | HPGD (0.73) | HPGDHSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL179025 | 0.86 | HPGD (0.84) | HPGDHSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31248383 | 0.85 | HSD17B10 (0.69) | HPGDHSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5191510 | 0.85 | HSD17B10 (0.69) | HPGDHSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5820481 | 0.85 | HPGD (0.68) | HPGDHSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3567133 | 0.85 | HPGD (0.68) | HPGDHSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5820488 | 0.85 | HPGD (0.68) | HPGDHSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4991673 | 0.84 | SMN1; SMN2 (0.73) | HPGDHSD17B10SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5189637 | 0.84 | HSD17B10 (0.67) | HPGDHSD17B10SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040410-A | Preparation method of piperonylethylamine | 湖北石河医药科技有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-116715652-A | Preparation method of key intermediate piperonylethylamine of berberine | 迪庆顺源生物有限公司 | 2023-09-08 | — | — | CN | disclosed |
| EP-2731608-B1 | INHIBITORS OF BACTERIAL TYPE III SECRETION SYSTEM | MICROBIOTIX INC (US) | 2018-03-14 | — | — | EP | disclosed |
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2012-04-12 | — | — | US | disclosed |
| US-7932264-B2 | Sinomenine derivatives and preparation and uses thereof | NATUREMED GROUP CORPORATION (US) | 2011-04-26 | — | — | US | disclosed |
| US-20080318966-A1 | Sinomenine Derivatives and Preparation and Uses Thereof | NIMBUS INNOWORKS LIMITED (CN) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PLOD3, COL1A1, THPO | HPGD 500/4885HSD17B10 2049/4885SMN1; SMN2 1774/4885 |
| US-20080318966-A1 | Sinomenine Derivatives and Preparation and Uses Thereof | OPRM1, SIN3A, MIF | HPGD 411/4885HSD17B10 3209/4885SMN1; SMN2 1786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.