Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20363329 | 0.97 | RIPK1 (0.62) | RIPK1EPHX2MMP8FAAHPOLB | |
| SCHEMBL20363306 | 0.86 | HPGD (0.57) | RIPK1EPHX2FAAHLMNARAB9A | |
| SCHEMBL20363286 | 0.86 | ALDH1A1 (0.57) | POLBSMN1; SMN2CNR1CNR2GAA | |
| SCHEMBL20363229 | 0.86 | RAB9A (0.50) | RIPK1POLBSMN1; SMN2GAALMNA | |
| SCHEMBL28477588 | 0.85 | RIPK1 (0.68) | RIPK1EPHX2MMP8FAAHPOLB | |
| SCHEMBL20363294 | 0.85 | RAB9A (0.49) | EPHX2POLBSMN1; SMN2LMNARAB9A | |
| SCHEMBL20363296 | 0.84 | RAB9A (0.51) | RIPK1POLBSMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL26667075 | 0.84 | RIPK1 (0.66) | RIPK1EPHX2MMP8FAAHPOLB | |
| SCHEMBL20363333 | 0.84 | ALDH1A1 (0.58) | RIPK1POLBSMN1; SMN2CNR1CNR2 | |
| SCHEMBL20363262 | 0.84 | HPGD (0.48) | RIPK1SMN1; SMN2LMNARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017522-B2 | Alpha helix mimetics and methods relating thereto | Prism BioLab Co., Ltd. (JP) | 2018-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017522-B2 | Alpha helix mimetics and methods relating thereto | PLOD3, COL1A1, THPO | RIPK1 4263/4885EPHX2 316/4885MMP8 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.