Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 7/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032988 | 0.86 | KDM1A (0.33) | BCHEKDM1AKCNH2HRH3 | |
| SCHEMBL1709436 | 0.86 | KDM4E (0.33) | — | |
| SCHEMBL10033181 | 0.86 | KDM4E (0.33) | — | |
| SCHEMBL1709440 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL10032983 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL1709418 | 0.81 | BCHE (0.32) | BCHE | |
| SCHEMBL10032973 | 0.78 | SIGMAR1 (0.38) | — | |
| SCHEMBL1709491 | 0.73 | KDM1A (0.42) | BCHEKDM1A | |
| SCHEMBL1709420 | 0.73 | SIGMAR1 (0.40) | KDM1A | |
| SCHEMBL10032826 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |