Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709420 | 0.90 | SIGMAR1 (0.40) | KDM1AMAOBMAOAGPR88SIGMAR1 | |
| SCHEMBL10032995 | 0.88 | HTR2A (0.34) | KDM1AMAOBMAOABCHEACHE | |
| SCHEMBL1709402 | 0.88 | HTR2C (0.34) | KDM1AMAOBMAOASIGMAR1 | |
| SCHEMBL10032988 | 0.87 | KDM1A (0.33) | KDM1AMAOBMAOABCHE | |
| SCHEMBL1709423 | 0.85 | ACHE (0.30) | KDM1AMAOBMAOAACHE | |
| SCHEMBL10033139 | 0.85 | SIGMAR1 (0.39) | KDM1AMAOBMAOASIGMAR1 | |
| SCHEMBL1709450 | 0.83 | HTR2C (0.33) | KDM1AMAOBMAOA | |
| SCHEMBL10032822 | 0.83 | HTR2C (0.33) | KDM1AMAOBMAOA | |
| SCHEMBL1709412 | 0.81 | OPRM1 (0.31) | KDM1AMAOBMAOABCHEACHE | |
| SCHEMBL10033004 | 0.80 | PSEN1 (0.36) | GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |