Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033124 | 0.89 | HSD11B1 (0.39) | HSD11B1MCHR1MGLLCYP3A4HTT | |
| SCHEMBL1709405 | 0.82 | TACR1 (0.38) | HSD11B1MCHR1MGLLHTR2AHTR2C | |
| SCHEMBL10032831 | 0.81 | TACR1 (0.36) | HSD11B1MCHR1MGLLHTR2AHTR2C | |
| SCHEMBL10032832 | 0.81 | TACR1 (0.36) | HSD11B1MCHR1MGLLHTR2AHTR2C | |
| SCHEMBL1709462 | 0.81 | DPEP1 (0.36) | HSD11B1MCHR1MGLLHTR2AHTR2C | |
| SCHEMBL1709509 | 0.81 | DPEP1 (0.36) | HSD11B1MCHR1MGLLHTR2AHTR2C | |
| SCHEMBL1709474 | 0.76 | ALDH1A1 (0.38) | HSD11B1MCHR1MGLLTACR1UBE2M | |
| SCHEMBL1709490 | 0.76 | ALDH1A1 (0.38) | HSD11B1MCHR1MGLLTACR1UBE2M | |
| SCHEMBL24913695 | 0.75 | PSEN1 (0.41) | HSD11B1MCHR1SLC6A4HTR2AHTR2C | |
| SCHEMBL10032998 | 0.74 | HTR2C (0.40) | HSD11B1MCHR1SLC6A4SLC6A3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |