Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032831 | 0.99 | TACR1 (0.36) | TACR1HSD11B1DPEP1MCHR1MGLL | |
| SCHEMBL10032832 | 0.99 | TACR1 (0.36) | TACR1HSD11B1DPEP1MCHR1MGLL | |
| SCHEMBL1709509 | 0.94 | DPEP1 (0.36) | TACR1HSD11B1DPEP1MCHR1MGLL | |
| SCHEMBL1709462 | 0.94 | DPEP1 (0.36) | TACR1HSD11B1DPEP1MCHR1MGLL | |
| SCHEMBL24913695 | 0.90 | PSEN1 (0.41) | TACR1HSD11B1DPEP1MCHR1HTR2A | |
| SCHEMBL1709409 | 0.88 | POLB (0.38) | HSD11B1DPEP1MGLLHTR2AHTR2C | |
| SCHEMBL1709408 | 0.86 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL1709407 | 0.86 | TP53 (0.39) | TACR1 | |
| SCHEMBL1709480 | 0.85 | NPC1 (0.38) | DGAT1 | |
| SCHEMBL1709454 | 0.85 | SLC6A2 (0.40) | TACR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |