Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.37 |
| ▸ | TP53 | P04637 | 5/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709408 | 0.89 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL1709407 | 0.89 | TP53 (0.39) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL1709409 | 0.88 | POLB (0.38) | RAB9AAGERDGAT1SMN1; SMN2 | |
| SCHEMBL1709358 | 0.87 | DPEP1 (0.36) | NPC1RAB9AMDM2TP53ALDH1A1 | |
| SCHEMBL10033001 | 0.87 | NPC1 (0.38) | NPC1RAB9AMDM2TP53ALDH1A1 | |
| SCHEMBL1709481 | 0.87 | MDM2 (0.43) | MDM2TP53 | |
| SCHEMBL10033121 | 0.86 | USP30 (0.38) | NPC1RAB9A | |
| SCHEMBL1709359 | 0.85 | USP30 (0.38) | NPC1RAB9AALDH1A1DGAT1SMN1; SMN2 | |
| SCHEMBL1709497 | 0.85 | EPHX2 (0.43) | ALDH1A1DGAT1SMN1; SMN2 | |
| SCHEMBL1709405 | 0.85 | TACR1 (0.38) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |