Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | AGER | Q15109 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709410 | 0.92 | POLB (0.35) | POLBRAB9ASMN1; SMN2SIGMAR1HSD11B1 | |
| SCHEMBL1709408 | 0.89 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL1709407 | 0.89 | TP53 (0.39) | RAB9ASMN1; SMN2MEN1KMT2APAX8 | |
| SCHEMBL1709480 | 0.88 | NPC1 (0.38) | RAB9ASMN1; SMN2AGERDGAT1 | |
| SCHEMBL1709359 | 0.88 | USP30 (0.38) | RAB9ASMN1; SMN2SLC6A2SLC6A4DGAT1 | |
| SCHEMBL1709405 | 0.88 | TACR1 (0.38) | HSD11B1DGAT1DPEP1HTR2AHTR2C | |
| SCHEMBL1709489 | 0.87 | OPRM1 (0.37) | SLC6A2SLC6A4DGAT1PKM | |
| SCHEMBL10032831 | 0.86 | TACR1 (0.36) | HSD11B1DGAT1DPEP1HTR2AHTR2C | |
| SCHEMBL10033121 | 0.86 | USP30 (0.38) | RAB9ASIGMAR1KMT2APAX8 | |
| SCHEMBL10032832 | 0.86 | TACR1 (0.36) | HSD11B1DGAT1DPEP1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |