Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032840 | 0.90 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1TDP1MEN1GAA | |
| SCHEMBL10033108 | 0.90 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1TDP1MEN1GAA | |
| SCHEMBL10033105 | 0.88 | TDP1 (0.36) | L3MBTL1ALDH1A1TDP1GPR88 | |
| SCHEMBL10032838 | 0.87 | TP53 (0.40) | L3MBTL1ALDH1A1TDP1MEN1GAA | |
| SCHEMBL10033115 | 0.86 | MDM2 (0.43) | L3MBTL1TP53MDM2 | |
| SCHEMBL1709437 | 0.84 | PTGES (0.37) | TDP1KMT2ATP53 | |
| SCHEMBL1709416 | 0.81 | KDM1A (0.44) | L3MBTL1HDAC6KDM1ASIGMAR1 | |
| SCHEMBL10033179 | 0.78 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL10033176 | 0.78 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1TDP1MEN1GAA | |
| SCHEMBL10032973 | 0.77 | SIGMAR1 (0.38) | TDP1MEN1KMT2ASIGMAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |