Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033175 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL10033185 | 0.71 | RECQL (0.33) | SMN1; SMN2 | |
| SCHEMBL10032971 | 0.70 | CYP11B1 (0.39) | CYP2D6KMT2AMEN1CYP11B1CYP11B2 | |
| SCHEMBL1709471 | 0.68 | KDM4E (0.40) | CYP11B1CYP11B2POLB | |
| SCHEMBL1709428 | 0.68 | CYP11B1 (0.43) | CYP11B1CYP11B2SMN1; SMN2POLB | |
| SCHEMBL1709483 | 0.68 | CYP11B1 (0.40) | CYP2D6KMT2AMEN1CYP11B1CYP11B2 | |
| SCHEMBL8276669 | 0.66 | CYP2D6 (0.45) | CYP2D6KMT2ACYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL1709470 | 0.65 | KDM4E (0.40) | CYP11B1CYP11B2POLB | |
| SCHEMBL1254599 | 0.65 | CYP2D6 (0.49) | CYP2D6KMT2ACYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL10032970 | 0.65 | CYP11B1 (0.40) | KMT2AMEN1CYP11B1CYP11B2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |