SCHEMBL10033175

SCHEMBL10033175

CCOC(=O)CC1CCCC(N(CCC2CCCCC2)CCC2CCCCC2)C1c1ccc(S(=O)#CO)cc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032977 0.81 MEN1 (0.38) ALDH1A1TDP1
SCHEMBL1709374 0.76 KMT2A (0.39) ALDH1A1TDP1
SCHEMBL10033185 0.73 RECQL (0.33) ALDH1A1
SCHEMBL1709493 0.71 CYP2D6 (0.37)
SCHEMBL10032828 0.71 ALDH1A1 (0.35) ALDH1A1TDP1
SCHEMBL1709474 0.70 ALDH1A1 (0.38) ALDH1A1TDP1
SCHEMBL1709490 0.70 ALDH1A1 (0.38) ALDH1A1TDP1
SCHEMBL10033069 0.70 MMP3 (0.36) ALDH1A1
SCHEMBL1709410 0.67 POLB (0.35)
SCHEMBL10033003 0.66 EPHX2 (0.45) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012046771-A1 CYCLOALKANE COMPOUND アステラス製薬株式会社 (JP) 2012-04-12 WO disclosed