Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13009581 | 0.88 | ESR2 (0.48) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13009578 | 0.87 | LMNA (0.40) | FFAR4ALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL1709504 | 0.87 | LMNA (0.40) | FFAR4ALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL8587317 | 0.86 | ALDH1A1 (0.47) | MEN1KMT2ATP53SMN1; SMN2HPGD | |
| SCHEMBL13008742 | 0.85 | CNR2 (0.45) | MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10032835 | 0.81 | FFAR4 (0.47) | TP53FFAR4 | |
| SCHEMBL13009582 | 0.79 | DRD2 (0.51) | FFAR4POLB | |
| SCHEMBL13169131 | 0.79 | DGAT1 (0.42) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL13009584 | 0.79 | DGAT1 (0.42) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL13009593 | 0.79 | DGAT1 (0.42) | MEN1KMT2AALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |