SCHEMBL17096505

SCHEMBL17096505

Cc1ccc(C2=Cc3c(cc(C)c(C)c3-c3ccccc3)C2[Zr](Cl)(Cl)(C2C(c3ccc(C)o3)=Cc3c2cc(C)c(C)c3-c2ccccc2)=[Si](C)C)o1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17060055 0.98 PTGS1 (0.33) PTGS1PTGS2
SCHEMBL17060062 0.96 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL17060176 0.93 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL17060102 0.93 PTGS1 (0.30) PTGS1PTGS2
SCHEMBL17097027 0.93 CHRM2 (0.30)
SCHEMBL17096948 0.93
SCHEMBL17097021 0.92 PTGS1 (0.31) PTGS1PTGS2
SCHEMBL17060184 0.92
SCHEMBL17096369 0.92
SCHEMBL17060081 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3121187-B1 METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER JAPAN POLYPROPYLENE CORP (JP) 2018-10-10 EP disclosed
US-9963522-B2 Metallocene complex and method for producing olefin polymer JAPAN POLYPROPYLENE CORPORATION (JP) 2018-05-08 US disclosed
US-9902749-B2 Metallocene complex and olefin polymerization method JAPAN POLYPROPYLENE CORPORATION (JP) 2018-02-27 US disclosed
US-20170081431-A1 METALLOCENE COMPLEX AND METHOD FOR PRODUCING OLEFIN POLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2017-03-23 US disclosed
EP-3121187-A1 METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER Japan Polypropylene Corporation (JP) 2017-01-25 EP disclosed
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORPORATION (JP) 2015-09-24 US disclosed
CN-104781270-A Metallocene complexes and olefin polymerization process JAPAN POLYPROPYLENE CORP 2015-07-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170081431-A1 METALLOCENE COMPLEX AND METHOD FOR PRODUCING OLEFIN POLYMER PPOX, ALOX12, PORCN PTGS1 266/4885PTGS2 176/4885
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD POR, OPRM1, ALOX12 PTGS1 201/4885PTGS2 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.