Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404539 | 0.94 | ACHE (0.46) | ACHEALDH1A1EPHX1 | |
| SCHEMBL7208796 | 0.84 | GRN (0.43) | ACHEALDH1A1EPHX1ITGB3ITGA2B | |
| SCHEMBL8591688 | 0.82 | ECE1 (0.43) | ACHEEPHX1ITGB3ITGA2B | |
| SCHEMBL9565515 | 0.82 | ECE1 (0.43) | ACHEEPHX1ITGB3ITGA2B | |
| SCHEMBL9103059 | 0.82 | EPHX1 (0.41) | ACHEALDH1A1EPHX1ITGB3ITGA2B | |
| SCHEMBL8872226 | 0.82 | ECE1 (0.43) | ACHEEPHX1ITGB3ITGA2B | |
| SCHEMBL9565518 | 0.82 | ACHE (0.44) | ACHEEPHX1 | |
| SCHEMBL480292 | 0.81 | EPHX1 (0.46) | ACHEALDH1A1EPHX1ITGB3ITGA2B | |
| SCHEMBL284168 | 0.81 | EPHX1 (0.46) | ACHEALDH1A1EPHX1ITGB3ITGA2B | |
| SCHEMBL9709088 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932382-B2 | Kv2.1 channel-derived peptides and methods of use | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170174740-A1 | KV2.1 CHANNEL-DERIVED PEPTIDES AND METHODS OF USE | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-06-22 | — | — | US | disclosed |
| WO-2015142826-A1 | KV2.1 CHANNEL-DERIVED PEPTIDES AND METHODS OF USE | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2015-09-24 | — | — | WO | disclosed |