Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708753 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BACEACE2CTSK | |
| SCHEMBL11789654 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7404539 | 0.85 | ACHE (0.46) | — | |
| SCHEMBL11397531 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BACEACE2 | |
| SCHEMBL17099347 | 0.80 | ACHE (0.41) | ITGB3ITGA2B | |
| SCHEMBL8586947 | 0.80 | ACE (0.44) | ITGB3ITGA2BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6254290 | 0.79 | CASP1 (0.57) | CTSKTDP1CASP1TSHRL3MBTL1 | |
| SCHEMBL4452037 | 0.79 | CASP1 (0.57) | CTSKTDP1CASP1TSHRL3MBTL1 | |
| SCHEMBL7758997 | 0.78 | ITGB3 (0.58) | ITGB3ITGA2BACEACE2CTSK | |
| SCHEMBL844471 | 0.78 | ITGB3 (0.58) | ITGB3ITGA2BACEACE2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011284-A1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES | THE JAMES BLACK FOUNDATION LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |