Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 4/20 | 0.43 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.38 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21063986 | 0.80 | DUT (0.43) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL16647505 | 0.79 | SLC28A1 (0.44) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL3478 | 0.79 | TK1 (0.49) | — | |
| SCHEMBL151326 | 0.78 | SLC28A1 (0.48) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL29824327 | 0.77 | DUT (0.39) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL2208242 | 0.76 | DUT (0.40) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL9548602 | 0.76 | SLC28A1 (0.46) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL9548604 | 0.76 | SLC28A1 (0.46) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL31653165 | 0.76 | SLC28A1 (0.46) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL18877290 | 0.76 | SLC28A1 (0.46) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081698-A1 | SURVIVAL ASSAYS FOR METAKARYOTIC STEM CELLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-03-23 | — | — | US | disclosed |
| WO-2015142827-A1 | SURVIVAL ASSAYS FOR METAKARYOTIC STEM CELLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-09-24 | — | — | WO | disclosed |