SCHEMBL9548602

SCHEMBL9548602

C[C@]1(CO)O[C@@H](n2ccc(=O)[nH]c2=O)C[C@@H]1O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.46
SLC28A2 O43868 1/20 0.46
SLC29A1 Q99808 1/20 0.46
SLC28A3 Q9HAS3 1/20 0.46
DUT P33316 5/20 0.43
P2RY2 P41231 6/20 0.39
P2RY6 Q15077 4/20 0.39
P2RY4 P51582 3/20 0.39
P2RY14 Q15391 1/20 0.38
TK1 P04183 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31653165 1.00 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL9548604 1.00 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL18877290 0.87 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL26135786 0.85 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL26136394 0.85 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL16647505 0.85 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL17533911 0.83 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL17534039 0.83 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL5189630 0.83 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3DUT
SCHEMBL21063986 0.83 DUT (0.43) SLC28A1SLC28A2SLC29A1SLC28A3DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4499106-A2 NUCLEOSIDE LINE-1 INHIBITORS Transposon Therapeutics, Inc. (US) 2025-02-05 EP claimed
WO-2023192491-A2 NUCLEOSIDE LINE-1 INHIBITORS TRANSPOSON THERAPEUTICS, INC. (US) 2023-10-05 WO claimed
US-20260035403-A1 NUCLEOSIDE LINE-1 INHIBITORS TRANSPOSON THERAPEUTICS, INC. (US) 2026-02-05 US disclosed
US-20230295212-A1 COMPOUNDS AND METHODS FOR TREATING DISEASE ROME THERAPEUTICS INC (US) 2023-09-21 US disclosed
EP-3466959-A1 SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF Janssen BioPharma, Inc. (US) 2019-04-10 EP disclosed
US-5192749-A Viricide, AIDS SYNTEX (U.S.A.) INC. (US) 1993-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295212-A1 COMPOUNDS AND METHODS FOR TREATING DISEASE EHMT1, POLRMT, RNASE1 SLC28A1 159/4885SLC28A2 603/4885SLC29A1 254/4885
US-20260035403-A1 NUCLEOSIDE LINE-1 INHIBITORS L3MBTL1, TDP1, TRDMT1 SLC28A1 6/4885SLC28A2 20/4885SLC29A1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.