Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22954280 | 0.88 | GRM4 (0.51) | GRM5NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL30117418 | 0.88 | GRM4 (0.51) | GRM5NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL5959942 | 0.82 | GRM5 (0.69) | GRM5NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL8252632 | 0.81 | GABRA1 (0.54) | GRM5NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL31187765 | 0.79 | GRM5 (0.49) | GRM5NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL17500184 | 0.79 | GRM5 (0.49) | GRM5NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL23526602 | 0.77 | GRM5 (0.48) | GRM5NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL31083655 | 0.77 | GRM5 (0.48) | GRM5NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL183897 | 0.76 | DYRK1A (0.66) | GRM5NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL29496945 | 0.76 | DYRK1A (0.66) | GRM5NPC1PKMRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745378-B2 | Antifungal compound process | Mycovia Pharmaceuticals, Inc. (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190161470-A1 | Antifungal Compound Process | MYCOVIA PHARMACEUTICALS INC (US) | 2019-05-30 | — | — | US | disclosed |
| US-10196375-B2 | Antifungal compound process | Mycovia Pharmaceuticals, Inc. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20170081310-A1 | ANTIFUNGAL COMPOUND PROCESS | Mycovia Pharmaceuticals, Inc. | 2017-03-23 | — | — | US | disclosed |
| EP-3119754-A1 | ANTIFUNGAL COMPOUND PROCESS | Viamet Pharmaceuticals, Inc. (US) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015143142-A1 | ANTIFUNGAL COMPOUND PROCESS | VIAMET PHARMACEUTICALS, INC. (US) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745378-B2 | Antifungal compound process | ERG28, DPM1, CYP51A1 | GRM5 3618/4885NPC1 29/4885PKM 2421/4885 |
| US-20170081310-A1 | ANTIFUNGAL COMPOUND PROCESS | ERG28, DPM1, CYP51A1 | GRM5 3618/4885NPC1 29/4885PKM 2421/4885 |
| US-20190161470-A1 | Antifungal Compound Process | ERG28, DPM1, CYP51A1 | GRM5 3618/4885NPC1 29/4885PKM 2421/4885 |
| US-10196375-B2 | Antifungal compound process | ERG28, DPM1, CYP51A1 | GRM5 3618/4885NPC1 29/4885PKM 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.