Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459628 | 0.75 | L3MBTL1 (0.43) | SMN1; SMN2L3MBTL1ALDH1A1BLMCYP2D6 | |
| SCHEMBL17490335 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1ALDH1A1BLMCYP2D6 | |
| SCHEMBL8329338 | 0.72 | PIN1 (0.42) | SMN1; SMN2L3MBTL1ALDH1A1BLMCYP2D6 | |
| SCHEMBL16132363 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1ALDH1A1BLMCYP2D6 | |
| SCHEMBL16132480 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1ALDH1A1BLMCYP2D6 | |
| SCHEMBL16059407 | 0.70 | BLM (0.41) | SMN1; SMN2L3MBTL1ALDH1A1BLMCYP2D6 | |
| SCHEMBL13269728 | 0.70 | L3MBTL1 (0.44) | SMN1; SMN2L3MBTL1ALDH1A1BLMCYP2D6 | |
| SCHEMBL28996741 | 0.70 | BLM (0.42) | SMN1; SMN2L3MBTL1ALDH1A1BLMCYP2D6 | |
| SCHEMBL7082456 | 0.69 | PPARG (0.40) | ALDH1A1CYP2D6OPRK1KCNH2CYP3A4 | |
| SCHEMBL7828236 | 0.69 | L3MBTL1 (0.47) | SMN1; SMN2L3MBTL1ALDH1A1BLMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015142903-A2 | METHOD OF CONTROLLING LACTATE PRODUCTION WITH PIPERDINE-DIONE DERIVATIVES | GENENTECH, INC. (US) | 2015-09-24 | — | — | WO | disclosed |
| US-20150079714-A1 | COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2015-03-19 | — | — | US | disclosed |