Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17100746 | 1.00 | KMT2A (0.48) | KMT2AMEN1L3MBTL1GBA1POLB | |
| SCHEMBL17100660 | 0.91 | ALDH1A1 (0.57) | KMT2AGBA1POLBALDH1A1LMNA | |
| SCHEMBL17100715 | 0.90 | L3MBTL1 (0.50) | KMT2AMEN1L3MBTL1GBA1POLB | |
| SCHEMBL17100888 | 0.90 | L3MBTL1 (0.50) | KMT2AMEN1L3MBTL1GBA1POLB | |
| SCHEMBL17100932 | 0.89 | L3MBTL1 (0.58) | KMT2AMEN1L3MBTL1GBA1POLB | |
| SCHEMBL17100917 | 0.89 | PKM (0.47) | KMT2AMEN1GBA1POLBALDH1A1 | |
| SCHEMBL17100769 | 0.89 | PTGDR (0.47) | POLBALDH1A1 | |
| SCHEMBL17100812 | 0.89 | TDP1 (0.48) | KMT2AMEN1L3MBTL1GBA1POLB | |
| SCHEMBL17100582 | 0.88 | GBA1 (0.47) | KMT2AMEN1GBA1POLBALDH1A1 | |
| SCHEMBL17100735 | 0.88 | ALDH1A1 (0.44) | POLBALDH1A1LMNAGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119774-A1 | OXADIAZOLE COMPOUNDS | reMynd NV (BE) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015140130-A1 | OXADIAZOLE COMPOUNDS | REMYND NV (BE) | 2015-09-24 | — | — | WO | disclosed |