SCHEMBL17100746

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17100716	1.00	KMT2A (0.48)	KMT2AMEN1L3MBTL1GBA1POLB
	SCHEMBL17100660	0.91	ALDH1A1 (0.57)	KMT2AGBA1POLBALDH1A1LMNA
	SCHEMBL17100715	0.90	L3MBTL1 (0.50)	KMT2AMEN1L3MBTL1GBA1POLB
	SCHEMBL17100888	0.90	L3MBTL1 (0.50)	KMT2AMEN1L3MBTL1GBA1POLB
	SCHEMBL17100932	0.89	L3MBTL1 (0.58)	KMT2AMEN1L3MBTL1GBA1POLB
	SCHEMBL17100917	0.89	PKM (0.47)	KMT2AMEN1GBA1POLBALDH1A1
	SCHEMBL17100769	0.89	PTGDR (0.47)	POLBALDH1A1
	SCHEMBL17100812	0.89	TDP1 (0.48)	KMT2AMEN1L3MBTL1GBA1POLB
	SCHEMBL17100582	0.88	GBA1 (0.47)	KMT2AMEN1GBA1POLBALDH1A1
	SCHEMBL17100735	0.88	ALDH1A1 (0.44)	POLBALDH1A1LMNAGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.