Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17100839 | 1.00 | DRD2 (0.40) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| SCHEMBL17115081 | 0.91 | HTR6 (0.39) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| SCHEMBL17100670 | 0.83 | L3MBTL1 (0.43) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| SCHEMBL17100793 | 0.83 | HTR6 (0.45) | DRD2DRD3SIGMAR1CETPHTR6 | |
| SCHEMBL17100749 | 0.83 | L3MBTL1 (0.43) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| SCHEMBL17100619 | 0.83 | OPRL1 (0.41) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| SCHEMBL17100725 | 0.82 | NPC1 (0.43) | SIGMAR1CETPHTR6NPC1RAB9A | |
| SCHEMBL17100861 | 0.82 | MAPT (0.40) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| SCHEMBL17100706 | 0.80 | MAPT (0.41) | HTR6RAB9AMAPK1L3MBTL1HTR2C | |
| SCHEMBL17100722 | 0.80 | SIGMAR1 (0.41) | DRD2DRD3SIGMAR1HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119774-A1 | OXADIAZOLE COMPOUNDS | reMynd NV (BE) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015140130-A1 | OXADIAZOLE COMPOUNDS | REMYND NV (BE) | 2015-09-24 | — | — | WO | disclosed |