Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17100749 | 1.00 | L3MBTL1 (0.43) | L3MBTL1ADRA1DADRA1AADRA1BHTR6 | |
| SCHEMBL17100793 | 0.90 | HTR6 (0.45) | L3MBTL1HTR6NPC1HTTRAB9A | |
| SCHEMBL17100613 | 0.90 | ABCC1 (0.42) | ADRA1DADRA1AADRA1BOPRL1RAB9A | |
| SCHEMBL17100725 | 0.89 | NPC1 (0.43) | L3MBTL1HTR6NPC1HTTRAB9A | |
| SCHEMBL17100964 | 0.86 | OPRL1 (0.43) | L3MBTL1ADRA1DADRA1AADRA1BOPRL1 | |
| SCHEMBL17100722 | 0.85 | SIGMAR1 (0.41) | ADRA1DADRA1AADRA1BOPRL1SIGMAR1 | |
| SCHEMBL21905673 | 0.85 | MAPT (0.53) | L3MBTL1HTR6NPC1HTTRAB9A | |
| SCHEMBL17100774 | 0.85 | ALDH1A1 (0.44) | L3MBTL1HTR6NPC1HTTRAB9A | |
| SCHEMBL18639406 | 0.85 | DRD2 (0.52) | ADRA1DADRA1AADRA1BOPRL1SIGMAR1 | |
| SCHEMBL17100959 | 0.85 | RAB9A (0.45) | L3MBTL1HTR6RAB9AMAPK1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119774-A1 | OXADIAZOLE COMPOUNDS | reMynd NV (BE) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015140130-A1 | OXADIAZOLE COMPOUNDS | REMYND NV (BE) | 2015-09-24 | — | — | WO | disclosed |