SCHEMBL17101017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17100888	0.91	L3MBTL1 (0.50)	ALDH1A1LMNAMAPK1TSHRPOLB
	SCHEMBL17100715	0.91	L3MBTL1 (0.50)	ALDH1A1LMNAMAPK1TSHRPOLB
	SCHEMBL17100660	0.89	ALDH1A1 (0.57)	ALDH1A1LMNAMAPK1TSHRPOLB
	SCHEMBL17100842	0.89	ALDH1A1 (0.59)	ALDH1A1LMNAMAPK1TSHRPOLB
	SCHEMBL17100713	0.89	PKM (0.57)	ALDH1A1LMNATSHRPOLBSMN1; SMN2
	SCHEMBL17100677	0.89	ALDH1A1 (0.46)	ALDH1A1LMNAMAPK1TSHRPOLB
	SCHEMBL17100640	0.86	LMNA (0.52)	ALDH1A1LMNAMAPK1TSHRPOLB
	SCHEMBL17100707	0.86	KMT2A (0.48)	ALDH1A1LMNAMAPK1TSHRPOLB
	SCHEMBL17100850	0.84	KMT2A (0.53)	ALDH1A1LMNATSHRPOLBSMN1; SMN2
	SCHEMBL17101010	0.82	PKM (0.56)	ALDH1A1LMNAMAPK1TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.