SCHEMBL5078683

SCHEMBL5078683

C(=Nc1cc(N=Cc2ccccc2)c(N=Cc2ccccc2)cc1N=Cc1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
ALDH1A1 P00352 3/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 2/20 0.52
HPGD P15428 1/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.50
HTT P42858 1/20 0.50
RAB9A P51151 1/20 0.50
BLM P54132 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CA1 P00915 4/20 0.49
CA2 P00918 4/20 0.49
CA12 O43570 3/20 0.49
CA9 Q16790 3/20 0.49
TSHR P16473 1/20 0.43
NOX1 Q9Y5S8 1/20 0.43
PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14524455 1.00 LMNA (0.55) LMNAL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL5078680 1.00 LMNA (0.55) LMNAL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL1870853 0.86 LMNA (0.59) LMNAL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL1710167 0.86 LMNA (0.59) LMNAL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL12633216 0.86 LMNA (0.59) LMNAL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL5082165 0.84 LMNA (0.44) LMNAL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL5085334 0.84 MAPT (0.51) LMNAL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL5484286 0.84 CA2 (0.50) LMNAL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL5484284 0.84 CA2 (0.50) LMNAL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL5085338 0.84 MAPT (0.51) LMNAL3MBTL1ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 EP disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-20070032556-A1 Aromatic polyamine derivative DAICEL CHEMICAL INSUSTRIES, LTD. (JP) 2007-02-08 US disclosed
EP-1683822-A1 PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM Daicel Chemical Industries, Ltd. (JP) 2006-07-26 EP disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032556-A1 Aromatic polyamine derivative SRM, PRMT1, KDM8 LMNA 3440/4885L3MBTL1 3091/4885ALDH1A1 179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.