SCHEMBL1710169

SCHEMBL1710169

O=C1OC(=O)c2ccc(S(=O)(=O)O)c3cccc1c23

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 6/20 0.54
AURKA O14965 1/20 0.49
AURKB Q96GD4 1/20 0.49
TTR P02766 1/20 0.43
SNCA P37840 2/20 0.40
CHAT P28329 1/20 0.40
ALOX15 P16050 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
COMT P21964 1/20 0.38
CYP1A2 P05177 2/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
USP2 O75604 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
POLB P06746 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
PABPC1 P11940 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30203973 1.00 TYMS (0.54) TYMSAURKAAURKBTTRSNCA
SCHEMBL3828946 0.87 AURKA (0.53) TYMSAURKAAURKBTTRSNCA
SCHEMBL15851430 0.84 AURKA (0.53) AURKAAURKBTTRSNCACHAT
SCHEMBL9479925 0.83 TYMS (0.59) TYMSALOX15TDP1CYP1A2MEN1
SCHEMBL6391678 0.82 TYMS (0.42) TYMSAURKAAURKBTTRSNCA
SCHEMBL8291788 0.81 POLB (0.56) AURKAAURKBALOX15TDP1CYP1A2
Potassium Ion SCHEMBL3736126 0.81 TYMS (0.53) TYMSALOX15TDP1CYP1A2MEN1
Potassium Ion SCHEMBL30617892 0.81 TYMS (0.53) TYMSALOX15TDP1CYP1A2MEN1
SCHEMBL6389483 0.81 TIMP3 (0.39) TYMSAURKAAURKBTTRTDP1
SCHEMBL11769544 0.80 TYMS (0.44) TYMSAURKAAURKBTTRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836116-A Novel PLK1 inhibitor and preparation method and application thereof 广西师范大学 2023-10-03 CN claimed
CN-115064385-A Manufacturing method of chip capacitor, polymerization solution and polymerization method 肇庆绿宝石电子科技股份有限公司 2022-09-16 CN claimed
CN-114864304-A Capacitor preparation process capable of reducing leakage current and capacitor 肇庆绿宝石电子科技股份有限公司 2022-08-05 CN claimed
CN-114694973-A Method for preparing conducting polymer by ultrasonic wave and solid capacitor 肇庆绿宝石电子科技股份有限公司 2022-07-01 CN claimed
CN-114664567-A Preparation method of chip capacitor unit with extremely low ESR 肇庆绿宝石电子科技股份有限公司 2022-06-24 CN claimed
CN-114664568-A Method for reducing equivalent series resistance of laminated capacitor 肇庆绿宝石电子科技股份有限公司 2022-06-24 CN claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 US claimed
JP-2007536237-A 2007-12-13 JP claimed
US-20070148124-A1 Cellulose and acrylic based polymers and the use thereof for the treatment of infectious diseases NOVAFLUX INC. 2007-06-28 US claimed
EP-1749041-A2 CELLULOSE AND ACRYLIC BASED POLYMERS AND THE USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES Nova Flux Biosciences, Inc. (US) 2007-02-07 EP claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
WO-2005111112-A2 CELLULOSE AND ACRYLIC BASED POLYMERS AND THE USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES NOVA FLUX BIOSCIENCES, INC. (US) 2005-11-24 WO claimed
US-20040242838-A1 Sulfonated polyester and process therewith DUAN JIWEN F (US) 2004-12-02 US claimed
JP-5222028-A None JP disclosed
US-4143020-A COPOLYMERS OF SULFONIC ACID MONOMERS ROHM AND HAAS COMPANY (US) 1979-03-06 US disclosed
US-4131736-A Polymers of sulfonic acid monomers ROHM AND HAAS COMPANY (US) 1978-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 TYMS 4322/4885AURKA 1397/4885AURKB 1294/4885
US-20070148124-A1 Cellulose and acrylic based polymers and the use thereof for the treatment of infectious diseases ALG1, CHIT1, CHIA TYMS 1838/4885AURKA 1882/4885AURKB 3127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.