Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.53 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196184 | 1.00 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL2511629 | 1.00 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL2516960 | 1.00 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL3338669 | 1.00 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL925671 | 1.00 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL1109721 | 1.00 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL3623095 | 1.00 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| Butane SCHEMBL1253088 | 0.98 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| Hydrochloric Acid SCHEMBL11274749 | 0.98 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL10930838 | 0.98 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11730938-B2 | Methods and compositions for treating skin | RODAN & FIELDS, LLC (US) | 2023-08-22 | — | — | US | disclosed |
| US-11717472-B2 | Skin cleansing device having interchangeable cleansing heads | RODAN & FIELDS, LLC (US) | 2023-08-08 | — | — | US | disclosed |
| US-20230031941-A1 | SKIN CLEANSING DEVICE HAVING INTERCHANGEABLE CLEANSING HEADS | ANKURA TRUST COMPANY, LLC, IN ITS CAPACITY AS SUCCESSOR AGENT | 2023-02-02 | — | — | US | disclosed |
| US-20210128898-A1 | METHODS AND COMPOSITIONS FOR TREATING SKIN | ANKURA TRUST COMPANY, LLC, IN ITS CAPACITY AS SUCCESSOR AGENT | 2021-05-06 | — | — | US | disclosed |
| US-10912934-B2 | Methods and compositions for treating skin | RODAN & FIELDS, LLC (US) | 2021-02-09 | — | — | US | disclosed |
| WO-2020150459-A1 | SKIN CLEANSING DEVICE HAVING INTERCHANGEABLE CLEANSING HEADS | RODAN & FIELDS, LLC (US) | 2020-07-23 | — | — | WO | disclosed |
| US-20200222269-A1 | SKIN CLEANSING DEVICE HAVING INTERCHANGEABLE CLEANSING HEADS | ANKURA TRUST COMPANY, LLC, IN ITS CAPACITY AS SUCCESSOR AGENT | 2020-07-16 | — | — | US | disclosed |
| US-20180326194-A1 | METHODS AND COMPOSITIONS FOR TREATING SKIN | ANKURA TRUST COMPANY, LLC, IN ITS CAPACITY AS SUCCESSOR AGENT | 2018-11-15 | — | — | US | disclosed |
| US-10052468-B1 | Methods and compositions for treating skin | RODAN & FIELDS, LLC (US) | 2018-08-21 | — | — | US | disclosed |
| US-9144434-B1 | Methods and compositions for treating skin | RODAN & FIELDS, LLC (US) | 2015-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10912934-B2 | Methods and compositions for treating skin | DSG1, CUTA, ERCC1 | LMNA 201/4885MAPT 1980/4885MAPK1 4537/4885 |
| US-11730938-B2 | Methods and compositions for treating skin | DSG1, CUTA, ERCC1 | LMNA 201/4885MAPT 1980/4885MAPK1 4537/4885 |
| US-20200222269-A1 | SKIN CLEANSING DEVICE HAVING INTERCHANGEABLE CLEANSING HEADS | CUTA, CFH, PIEZO1 | LMNA 4115/4885MAPT 4285/4885MAPK1 3065/4885 |
| US-11717472-B2 | Skin cleansing device having interchangeable cleansing heads | CUTA, CFH, PIEZO1 | LMNA 4115/4885MAPT 4285/4885MAPK1 3065/4885 |
| US-20230031941-A1 | SKIN CLEANSING DEVICE HAVING INTERCHANGEABLE CLEANSING HEADS | CUTA, CFH, PIEZO1 | LMNA 4115/4885MAPT 4285/4885MAPK1 3065/4885 |
| US-20180326194-A1 | METHODS AND COMPOSITIONS FOR TREATING SKIN | DSG1, CUTA, ERCC1 | LMNA 201/4885MAPT 1980/4885MAPK1 4537/4885 |
| US-10052468-B1 | Methods and compositions for treating skin | DSG1, CUTA, ERCC1 | LMNA 201/4885MAPT 1980/4885MAPK1 4537/4885 |
| US-20210128898-A1 | METHODS AND COMPOSITIONS FOR TREATING SKIN | DSG1, CUTA, ERCC1 | LMNA 201/4885MAPT 1980/4885MAPK1 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.