Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17103219 | 0.82 | KMT2A (0.52) | MEN1KMT2AMAPTHPGDHTT | |
| SCHEMBL5170350 | 0.80 | MEN1 (0.48) | MEN1KMT2AMAPTMAPK1MMP1 | |
| SCHEMBL1532248 | 0.79 | KMT2A (0.59) | MEN1KMT2AMAPTHPGDHTT | |
| SCHEMBL13305747 | 0.76 | MAPT (0.47) | MEN1KMT2AMAPTHPGDHTT | |
| SCHEMBL3576370 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL1478058 | 0.74 | ALDH1A1 (0.53) | MEN1KMT2AMAPTHPGDHTT | |
| SCHEMBL1454638 | 0.74 | MAPT (0.52) | MEN1KMT2AMAPTHPGDHTT | |
| SCHEMBL16412251 | 0.73 | KDM4E (0.49) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL7196335 | 0.73 | MAPT (0.51) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL4740981 | 0.73 | MEN1 (0.54) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2924021-B1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | UNIV SICHUAN (CN) | 2019-08-28 | — | — | EP | disclosed |
| US-9402819-B2 | Anti-HIV compound and preparation method and use thereof | SICHUAN UNIVERSITY (CN) | 2016-08-02 | — | — | US | disclosed |
| US-9402819-B2 | Anti-HIV compound and preparation method and use thereof | SICHUAN UNIVERSITY (CN) | 2016-08-02 | — | — | US | disclosed |
| US-9402819-B2 | Anti-HIV compound and preparation method and use thereof | SICHUAN UNIVERSITY (CN) | 2016-08-02 | — | — | US | disclosed |
| US-20150313853-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN UNIVERSITY (CN) | 2015-11-05 | — | — | US | disclosed |
| US-20150313853-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN UNIVERSITY (CN) | 2015-11-05 | — | — | US | disclosed |
| US-20150313853-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN UNIVERSITY (CN) | 2015-11-05 | — | — | US | disclosed |
| EP-2924021-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | Sichuan University (CN) | 2015-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150313853-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | FURIN, CD4, SI | MEN1 3628/4885KMT2A 3442/4885MAPT 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.