Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17104265 | 0.82 | CHRM1 (0.34) | CHRM1MEN1NPBWR1KMT2AGRIN1 | |
| SCHEMBL1313862 | 0.80 | ALOX15 (0.36) | CHRM1 | |
| SCHEMBL1313248 | 0.77 | NOTUM (0.31) | — | |
| SCHEMBL1313749 | 0.65 | — | — | |
| SCHEMBL615680 | 0.65 | SLC6A4 (0.43) | CHRM1SLC6A4ALDH1A1SIGMAR1 | |
| SCHEMBL1313864 | 0.64 | ALOX15 (0.37) | CHRM1 | |
| SCHEMBL4157539 | 0.64 | CHRM1 (0.41) | CHRM1SLC6A4ALDH1A1SIGMAR1 | |
| SCHEMBL1313859 | 0.62 | PYGL (0.41) | CHRM1MEN1KMT2ASLC6A4 | |
| SCHEMBL4216794 | 0.62 | SLC6A4 (0.36) | CHRM1MEN1KMT2ASLC6A4ALDH1A1 | |
| SCHEMBL4205032 | 0.62 | SLC6A4 (0.36) | CHRM1MEN1KMT2ASLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292613-B1 | DIHYDROINDOLINONE DERIVATIVES | SHANGHAI INST PHARM INDUSTRY (CN) | 2015-09-30 | — | — | EP | disclosed |