Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | PPARG | P37231 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.65 |
| ▸ | GLA | P06280 | 7/20 | 0.65 |
| ▸ | GAA | P10253 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711024 | 0.89 | ALDH1A1 (0.76) | MAOBPPARGALDH1A1KDM4EGLA | |
| SCHEMBL2508806 | 0.88 | MAOB (0.64) | MAOBPPARGALDH1A1KDM4EGLA | |
| SCHEMBL2510193 | 0.87 | ALDH1A1 (0.65) | MAOBPPARGALDH1A1KDM4EGLA | |
| SCHEMBL1710937 | 0.87 | ALDH1A1 (0.65) | MAOBPPARGALDH1A1KDM4EGLA | |
| SCHEMBL2510780 | 0.87 | ALDH1A1 (0.65) | MAOBPPARGALDH1A1KDM4EGLA | |
| SCHEMBL17083907 | 0.86 | PPARG (0.70) | MAOBPPARGALDH1A1KDM4EGLA | |
| SCHEMBL1711220 | 0.86 | PPARG (0.73) | MAOBPPARGALDH1A1KDM4EGLA | |
| SCHEMBL28014855 | 0.82 | ALDH1A1 (0.67) | MAOBPPARGALDH1A1KDM4EGAA | |
| SCHEMBL28471066 | 0.81 | PPARG (1.00) | MAOBPPARGALDH1A1KDM4EGLA | |
| SCHEMBL10702057 | 0.81 | MAOB (1.00) | MAOBPPARGALDH1A1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951034-B2 | 3-ketocoumarines for LED photocuring | IGM RESINS ITALIA S.R.L. (IT) | 2018-04-24 | — | — | US | disclosed |
| US-9951034-B2 | 3-ketocoumarines for LED photocuring | IGM RESINS ITALIA S.R.L. (IT) | 2018-04-24 | — | — | US | disclosed |
| EP-2344462-B1 | PYRIMIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | UNIV DUNDEE (GB) | 2016-05-18 | — | — | EP | disclosed |
| US-20150259316-A1 | 3-KETOCOUMARINES FOR LED PHOTOCURING | ELIOS S.R.L. (IT) | 2015-09-17 | — | — | US | disclosed |
| US-20150259316-A1 | 3-KETOCOUMARINES FOR LED PHOTOCURING | ELIOS S.R.L. (IT) | 2015-09-17 | — | — | US | disclosed |
| US-8563557-B2 | Pyrimidine derivatives and their pharmaceutical use | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2013-10-22 | — | — | US | disclosed |
| US-20110245282-A1 | Compounds | University Court of the University of Dundee University Court of the University of St. Andrews | 2011-10-06 | — | — | US | disclosed |
| EP-2344462-A1 | PYRIMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE | The University Court of the University of Dundee (GB) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010038043-A1 | PYRIMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE | THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245282-A1 | Compounds | NAT1, AR, ARSA | MAOB 926/4885PPARG 354/4885ALDH1A1 1954/4885 |
| US-20150259316-A1 | 3-KETOCOUMARINES FOR LED PHOTOCURING | KDM3A, KMO, HCCS | MAOB 1444/4885PPARG 3436/4885ALDH1A1 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.