SCHEMBL17109999

SCHEMBL17109999

c1cc(-c2ccc3c4ccccc4n(-c4ccc5sc6ccccc6c5c4)c3c2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GPR3 P46089 1/20 0.37
MAPT P10636 4/20 0.36
RAB9A P51151 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PIM3 Q86V86 1/20 0.32
ALOX5 P09917 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
CYP1A2 P05177 1/20 0.32
HSD17B10 Q99714 1/20 0.31
HDAC4 P56524 1/20 0.30
PTPN7 P35236 1/20 0.30
DUSP3 P51452 1/20 0.30
PTPN12 Q05209 1/20 0.30
PTPN22 Q9Y2R2 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24039425 0.97 ATM (0.41) KDM4EATML3MBTL1GPR3MAPT
SCHEMBL17110016 0.96 KDM4E (0.41) KDM4EATML3MBTL1GPR3MAPT
SCHEMBL17110017 0.95 ATM (0.41) KDM4EATML3MBTL1GPR3MAPT
SCHEMBL16409620 0.95 KDM4E (0.40) KDM4EATML3MBTL1GPR3MAPT
SCHEMBL16409587 0.95 KDM4E (0.40) KDM4EATML3MBTL1GPR3MAPT
SCHEMBL16641517 0.94 ATM (0.39) KDM4EATML3MBTL1GPR3MAPT
SCHEMBL25941157 0.94 ATM (0.39) KDM4EATML3MBTL1GPR3MAPT
SCHEMBL25671960 0.94 ATM (0.39) KDM4EATML3MBTL1GPR3MAPT
SCHEMBL12088856 0.94 KDM4E (0.36) KDM4EATML3MBTL1GPR3MAPT
SCHEMBL17562337 0.94 KDM4E (0.39) KDM4EATML3MBTL1GPR3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11075343-B2 Organic light emitting compounds and organic light emitting devices including the same SFC CO., LTD. (KR) 2021-07-27 US disclosed
US-10208026-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-02-19 US disclosed
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-07-20 US disclosed
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-07-20 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 EP disclosed
US-20150266863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-24 US disclosed
US-20150266863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 KDM4E 3396/4885ATM 2966/4885L3MBTL1 2272/4885
US-11075343-B2 Organic light emitting compounds and organic light emitting devices including the same HARS1, ALDH1A2, NR2E3 KDM4E 3813/4885ATM 4125/4885L3MBTL1 562/4885
US-10208026-B2 Organic electroluminescent materials and devices ZYX, LBR, LOXL1 KDM4E 3364/4885ATM 3634/4885L3MBTL1 26/4885
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME HARS1, ALDH1A2, ALDH1A3 KDM4E 3906/4885ATM 4456/4885L3MBTL1 451/4885
US-20150266863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ZYX, LBR, LOXL1 KDM4E 3364/4885ATM 3634/4885L3MBTL1 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.