Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711027 | 1.00 | MAOB (0.46) | MAOBCYP1A2CYP1B1CYP2D6ATM | |
| SCHEMBL1711334 | 0.79 | MAOB (0.46) | MAOBCYP1A2CYP1B1CYP2D6NFE2L2 | |
| SCHEMBL1711332 | 0.79 | MAOB (0.46) | MAOBCYP1A2CYP1B1CYP2D6NFE2L2 | |
| SCHEMBL20544339 | 0.77 | HSP90AA1 (0.52) | CYP1A2CYP2D6RECQLMAPTHPGD | |
| SCHEMBL20544340 | 0.77 | HSP90AA1 (0.52) | CYP1A2CYP2D6RECQLMAPTHPGD | |
| SCHEMBL149579 | 0.74 | MAOB (0.59) | MAOBCYP1A2CYP1B1CYP2D6NFE2L2 | |
| SCHEMBL149581 | 0.74 | MAOB (0.59) | MAOBCYP1A2CYP1B1CYP2D6NFE2L2 | |
| SCHEMBL29900779 | 0.74 | MAOB (0.59) | MAOBCYP1A2CYP1B1CYP2D6NFE2L2 | |
| SCHEMBL7240982 | 0.72 | NFE2L2 (0.58) | MAOBNFE2L2HPGDALDH1A1RAB9A | |
| SCHEMBL3581314 | 0.71 | NFE2L2 (0.62) | MAOBCYP1A2CYP1B1CYP2D6NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150510-B2 | Amino acid derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-06 | — | — | US | disclosed |
| CN-102216260-B | Amino acid derivative | NIPPON ZOKI PHARMACEUTICAL CO | 2015-07-15 | — | — | CN | disclosed |
| EP-2345635-A1 | AMINO ACID DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20110172442-A1 | AMINO ACID DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172442-A1 | AMINO ACID DERIVATIVE | OPRL1, OPRK1, SLC1A1 | MAOB 3354/4885CYP1A2 3676/4885CYP1B1 4397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.