SCHEMBL20544339

SCHEMBL20544339

O=C(/C=C/c1ccccc1)ON1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.52
KMT2A Q03164 6/20 0.51
MEN1 O00255 2/20 0.51
LMNA P02545 2/20 0.47
MAPT P10636 4/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
ALDH1A1 P00352 2/20 0.47
HDAC3 O15379 1/20 0.47
TNKS O95271 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HCAR2 Q8TDS4 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
TNKS2 Q9H2K2 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20544340 1.00 HSP90AA1 (0.52) HSP90AA1KMT2AMEN1LMNAMAPT
SCHEMBL7213005 0.92 LMNA (0.52) HSP90AA1KMT2AMEN1LMNAMAPT
SCHEMBL28602892 0.86 KMT2A (0.46) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL28347103 0.84 RAB9A (0.61) HSP90AA1KMT2AMEN1LMNAMAPT
SCHEMBL9724555 0.84 POLB (0.61) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL1711027 0.77 MAOB (0.46) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL1711028 0.77 MAOB (0.46) KMT2AMEN1LMNAMAPTSMN1; SMN2
SCHEMBL5874735 0.76 ALDH1A1 (0.35) ALDH1A1HCAR2POLBHPGD
SCHEMBL5875212 0.76 ALDH1A1 (0.35) ALDH1A1HCAR2POLBHPGD
SCHEMBL692499 0.75 MEN1 (0.87) HSP90AA1KMT2AMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2687371-B1 LAMINATE, METHOD FOR MANUFACTURING SAME, AND MOLDED CONTAINER TOPPAN PRINTING CO LTD (JP) 2018-10-31 EP disclosed