Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 3/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17110302 | 0.90 | ALDH1A1 (0.33) | ALDH1A1MAPTHDAC1HDAC6NTRK1 | |
| SCHEMBL17110301 | 0.85 | ALDH1A1 (0.33) | LPAR1LPAR5ALDH1A1MAPTHDAC1 | |
| SCHEMBL17110314 | 0.84 | ALDH1A1 (0.32) | ALDH1A1MAPTNTRK1 | |
| SCHEMBL17110303 | 0.84 | ALDH1A1 (0.34) | ALDH1A1MAPTHDAC1HDAC6MEN1 | |
| SCHEMBL17110284 | 0.83 | ALDH1A1 (0.30) | ALDH1A1MAPT | |
| SCHEMBL17110300 | 0.82 | LPAR1 (0.31) | LPAR1LPAR5ALDH1A1MAPTNTRK1 | |
| SCHEMBL17110313 | 0.82 | ALDH1A1 (0.32) | ALDH1A1MAPTKMT2ANTRK1 | |
| SCHEMBL17110308 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPTMEN1KMT2ANTRK1 | |
| SCHEMBL17097660 | 0.81 | LPAR1 (0.35) | LPAR1LPAR5ALDH1A1MAPTHCRTR2 | |
| SCHEMBL17048992 | 0.81 | LPAR1 (0.35) | LPAR1LPAR5ALDH1A1MAPTHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365522-B2 | Pyrazole amide derivative | AMGEN INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150266824-A1 | Pyrazole Amide Derivative | TEIJIN LIMITED (JP) | 2015-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266824-A1 | Pyrazole Amide Derivative | RORC, RORB, RORA | LPAR1 2474/4885LPAR5 1505/4885ALDH1A1 923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.