Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | UBE2M | P61081 | 2/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17099203 | 0.93 | ALDH1A1 (0.31) | ALDH1A1MAPTPTPN1CCR5UBE2M | |
| SCHEMBL17099204 | 0.93 | ALDH1A1 (0.31) | ALDH1A1MAPTPTPN1CCR5UBE2M | |
| SCHEMBL17099201 | 0.93 | ALDH1A1 (0.31) | ALDH1A1MAPTPTPN1CCR5UBE2M | |
| SCHEMBL17097761 | 0.93 | ALDH1A1 (0.32) | ALDH1A1MAPTPTPN1CCR5UBE2M | |
| SCHEMBL17097762 | 0.93 | ALDH1A1 (0.32) | ALDH1A1MAPTPTPN1CCR5UBE2M | |
| SCHEMBL17097764 | 0.93 | ALDH1A1 (0.32) | ALDH1A1MAPTPTPN1CCR5UBE2M | |
| SCHEMBL17098423 | 0.88 | ALDH1A1 (0.32) | ALDH1A1MAPTPTPN1CCR5UBE2M | |
| SCHEMBL17098422 | 0.88 | ALDH1A1 (0.32) | ALDH1A1MAPTPTPN1CCR5UBE2M | |
| SCHEMBL17098424 | 0.88 | ALDH1A1 (0.32) | ALDH1A1MAPTPTPN1CCR5UBE2M | |
| SCHEMBL17098897 | 0.88 | ALDH1A1 (0.34) | ALDH1A1MAPTPTPN1CCR5PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365522-B2 | Pyrazole amide derivative | AMGEN INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9365522-B2 | Pyrazole amide derivative | AMGEN INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150266824-A1 | Pyrazole Amide Derivative | TEIJIN LIMITED (JP) | 2015-09-24 | — | — | US | disclosed |
| US-20150266824-A1 | Pyrazole Amide Derivative | TEIJIN LIMITED (JP) | 2015-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266824-A1 | Pyrazole Amide Derivative | RORC, RORB, RORA | ALDH1A1 923/4885MAPT 3584/4885PTPN1 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.