Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818231 | 0.87 | PARP1 (0.37) | EP300CA1CA2PARP1PTPN1 | |
| SCHEMBL18352309 | 0.82 | TRPM4 (0.39) | EP300CA1TP53KMT2AGAA | |
| SCHEMBL15895856 | 0.82 | IDO1 (0.40) | EP300CA1CA2CA4CA6 | |
| SCHEMBL1812200 | 0.82 | PDK2 (0.48) | EP300PTPN1HSP90AA1LMNA | |
| SCHEMBL9898722 | 0.81 | CYP1A1 (0.47) | EP300HSP90AA1HSP90AB1KMT2AMEN1 | |
| SCHEMBL1711096 | 0.81 | PRKDC (0.40) | TP53TSHRGAAL3MBTL1LMNA | |
| SCHEMBL30125362 | 0.80 | PDK2 (0.40) | EP300CA1CA2TP53TSHR | |
| SCHEMBL165110 | 0.80 | PDK2 (0.40) | EP300CA1CA2TP53TSHR | |
| SCHEMBL18352478 | 0.79 | IDO1 (0.38) | EP300CA1CA2CA4CA6 | |
| SCHEMBL12859979 | 0.79 | HTT (0.45) | EP300CA1TP53KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606274-B9 | INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS, NAPHTHOLS AND PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-1606274-B1 | INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS, NAPHTHOLS AND PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-2345648-B1 | Indeno-fused photochromic naphthopyrans, naphthols and photochromic articles | TRANSITIONS OPTICAL INC (US) | 2012-10-24 | — | — | EP | disclosed |
| EP-2345648-A1 | Indeno-fused photochromic naphthopyrans, naphthols and photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-2345647-A2 | Indeno-fused photochromic naphthopyrans, naphthols and photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2011-07-20 | — | — | EP | disclosed |
| US-7557208-B2 | Naphthols useful for preparing indeno-fused photochromic naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-7517982-B2 | Naphthols useful for preparing indeno-fused photochromic naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 2009-04-14 | — | — | US | disclosed |
| US-20090062533-A1 | NAPHTHOLS USEFUL FOR PREPARING INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2009-03-05 | — | — | US | disclosed |
| US-7262295-B2 | Indeno-fused photochromic naphthopyrans, naphthols and photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-20070155964-A1 | Naphthols useful for preparing indeno-fused photochromic naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2007-07-05 | — | — | US | disclosed |
| US-20040185255-A1 | Indeno-fused photochromic naphthopyrans, naphthols and photochromic articles | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | disclosed |
| EP-1214311-B1 | NOVEL INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6296785-B1 | OPHTHALMIC AND CONTACT LENSES; WINDOWS, SAFETY GLASS FOR CARS | PPG INDUSTRIES OHIO, INC. | 2001-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040185255-A1 | Indeno-fused photochromic naphthopyrans, naphthols and photochromic articles | IPO4, NPM1, PPOX | EP300 2707/4885CA1 4169/4885CA2 3585/4885 |
| US-20070155964-A1 | Naphthols useful for preparing indeno-fused photochromic naphthopyrans | IPO5, IPO4, NQO1 | EP300 2170/4885CA1 4785/4885CA2 4751/4885 |
| US-20090062533-A1 | NAPHTHOLS USEFUL FOR PREPARING INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS | IPO5, IPO4, NQO1 | EP300 2170/4885CA1 4785/4885CA2 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.