Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 3/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.47 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.47 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.47 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.47 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.47 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4F8 | P98187 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812200 | 0.90 | PDK2 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C19KDM4E | |
| SCHEMBL9898302 | 0.89 | HSP90AA1 (0.44) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL1814886 | 0.88 | PDK2 (0.46) | MEN1KMT2AKDM4EPOLBESR2 | |
| SCHEMBL1813707 | 0.83 | MEN1 (0.42) | MEN1KMT2AKDM4EPOLBPDK2 | |
| SCHEMBL1711142 | 0.81 | EP300 (0.45) | MEN1KMT2AESR1ESR2HSP90AA1 | |
| SCHEMBL8513816 | 0.81 | PDK2 (0.47) | CYP1A2CYP3A4CYP2D6CYP2C19MEN1 | |
| SCHEMBL30125488 | 0.81 | PDK2 (0.47) | CYP1A2CYP3A4CYP2D6CYP2C19MEN1 | |
| SCHEMBL16301275 | 0.80 | PDK2 (0.38) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL1010429 | 0.79 | ALK (0.40) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL161727 | 0.79 | ALOX5 (0.39) | MEN1KMT2AKDM4EESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9028728-B2 | Photochromic materials that include indeno-fused naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| WO-2013086248-A1 | PHOTOCHROMIC MATERIALS THAT INCLUDE INDENO-FUSED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 2013-06-13 | — | — | WO | disclosed |
| US-20120145973-A1 | Photochromic Materials That Include Indeno-Fused Naphthopyrans | TRANSITIONS OPTICAL INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120145973-A1 | Photochromic Materials That Include Indeno-Fused Naphthopyrans | NQO1, INTS6, IPO4 | CYP1A1 38/4885CYP1B1 60/4885CYP1A2 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.