Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 3/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421 | 0.84 | TSHR (0.47) | TSHRTDP1ZDHHC20ZDHHC2TGM2 | |
| SCHEMBL8185037 | 0.84 | TSHR (0.47) | TSHRTDP1ZDHHC20ZDHHC2TGM2 | |
| SCHEMBL23870419 | 0.82 | PSMB5 (0.43) | TSHRPOLBALDH1A1MAPK1TDP1 | |
| SCHEMBL28459310 | 0.82 | POLB (0.38) | POLBALDH1A1MMEKDM4EMAPT | |
| SCHEMBL8186011 | 0.81 | TGM2 (0.50) | TSHRMAPK1ZDHHC20ZDHHC2TGM2 | |
| SCHEMBL1562504 | 0.81 | TGM2 (0.50) | TSHRMAPK1ZDHHC20ZDHHC2TGM2 | |
| SCHEMBL6513640 | 0.81 | TGFBR1 (0.52) | TSHRALDH1A1MAPK1TDP1TGFBR1 | |
| SCHEMBL6513633 | 0.81 | TGFBR1 (0.52) | TSHRALDH1A1MAPK1TDP1TGFBR1 | |
| SCHEMBL8188102 | 0.80 | ALDH1A1 (0.60) | TSHRALDH1A1MAPTFOLH1NAALAD2 | |
| SCHEMBL27828839 | 0.80 | ALDH1A1 (0.60) | TSHRALDH1A1MAPTFOLH1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | ALCON INC. (CH) | 2026-05-26 | — | — | US | claimed |
| EP-4514596-B1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| EP-4369081-B1 | METHOD FOR PRODUCING AN OPHTHALMIC PRODUCT | ALCON INC (CH) | 2025-06-25 | — | — | EP | claimed |
| US-12247169-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2025-03-11 | — | — | US | claimed |
| EP-4514597-A1 | METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES | Alcon Inc. (CH) | 2025-03-05 | — | — | EP | claimed |
| EP-4514596-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2025-03-05 | — | — | EP | claimed |
| US-12116442-B2 | Method for producing silicone hydrogel contact lenses | ALCON INC. (CH) | 2024-10-15 | — | — | US | claimed |
| US-20240287379-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2024-08-29 | — | — | US | claimed |
| US-11999908-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2024-06-04 | — | — | US | claimed |
| EP-4146461-B1 | METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-03-13 | — | — | EP | claimed |
| CN-114981072-A | Wettable silicone hydrogel contact lenses | 爱尔康公司 | 2022-08-30 | — | — | CN | claimed |
| CN-114502362-A | Contact lenses with surfaces of varying softness | 爱尔康公司 | 2022-05-13 | — | — | CN | claimed |
| CN-110831990-B | Poly (meth) acrylamide-based copolymers with carboxyl-terminated side chains | 爱尔康公司 | 2022-02-01 | — | — | CN | claimed |
| EP-1435380-B1 | Polymer additive for ink-jet inks to improve durability | HEWLETT PACKARD DEVELOPMENT CO (US) | 2008-04-16 | — | — | EP | claimed |
| US-6858301-B2 | Specific core-shell polymer additive for ink-jet inks to improve durability | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2005-02-22 | — | — | US | claimed |
| US-20040131855-A1 | SPECIFIC CORE-SHELL POLYMER ADDITIVE FOR INK-JET INKS TO IMPROVE DURABILITY | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2004-07-08 | — | — | US | claimed |
| EP-1435380-A1 | Polymer additive for ink-jet inks to improve durability | Hewlett-Packard Development Company, L.P. (US) | 2004-07-07 | — | — | EP | claimed |
| US-6716949-B2 | PREPARED BY POLYMERIZING AT LEAST AN UNSATURATED HYDROPHOBIC MONOMER, AND AN UNSATURATED MONOMER CONTAINING A CONVERTIBLE MOIETY THAT IS HYDROPHOBIC IN AN ACIDIC ENVIRONMENT AND HYDROPHILIC IN A BASIC ENVIRONMENT. | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2004-04-06 | — | — | US | claimed |
| US-20030198648-A1 | Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA | ACHILION PHARMACEUTICALS | 2003-10-23 | — | — | US | claimed |
| WO-2003060098-A2 | METHODS FOR IDENTIFYING COMPOUNDS WHICH INHIBIT BINDING OF NUCLEOCAPSID 7 PROTEIN TO HIV-1 RNA | ACHILLION PHARMACEUTICALS, INC. (US) | 2003-07-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | SMCHD1, CRYAA, CRYZ | TSHR 1465/4885POLB 2857/4885ALDH1A1 2364/4885 |
| US-20030198648-A1 | Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA | MRPS27, SNRPE, NSUN2 | TSHR 4796/4885POLB 255/4885ALDH1A1 4104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.