Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12612709 | 0.81 | MAPT (0.39) | MAPTNPSR1ALDH1A1KMT2ARAB9A | |
| SCHEMBL12613125 | 0.77 | MAPT (0.40) | MAPTNPSR1ALDH1A1KMT2ARAB9A | |
| SCHEMBL19260943 | 0.72 | NPY1R (0.48) | KMT2ARAB9AMEN1KIF18ANPY1R | |
| SCHEMBL5270336 | 0.69 | MET (0.46) | MAPTALDH1A1KMT2AMEN1GFER | |
| SCHEMBL17113647 | 0.69 | MET (0.49) | NPSR1KMT2AMETLMNANAMPT | |
| SCHEMBL2043670 | 0.68 | KMT2A (0.46) | MAPTNPSR1ALDH1A1KMT2ARAB9A | |
| SCHEMBL28003201 | 0.67 | IKBKB (0.42) | MAPTALDH1A1METJAK2IKBKB | |
| SCHEMBL28040158 | 0.66 | EGFR (0.53) | METJAK2IKBKBCHUK | |
| SCHEMBL18497228 | 0.65 | TXNRD1 (0.67) | MAPTNPSR1ALDH1A1KMT2ARAB9A | |
| SCHEMBL12613146 | 0.65 | IKBKB (0.36) | MAPTALDH1A1KMT2AMETLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122731-A1 | NEW COMPOUNDS | Novartis Tiergesundheit AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| WO-2015144773-A1 | NEW COMPOUNDS | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-10-01 | — | — | WO | disclosed |