Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85996 | 0.86 | MAOB (0.62) | MAOBNPC1RAB9AMAOAKDM4E | |
| SCHEMBL17115258 | 0.77 | ROCK2 (0.37) | ROCK2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL11209858 | 0.75 | MAPT (0.70) | ROCK2MAOBCYP11B1NPC1RAB9A | |
| SCHEMBL22868035 | 0.75 | NPC1 (0.71) | ROCK2CYP11B1NPC1RAB9AMAOA | |
| SCHEMBL7097279 | 0.75 | KDM4E (0.69) | MAOBNPC1RAB9AMAOAKDM4E | |
| SCHEMBL7014663 | 0.75 | MAOB (0.50) | MAOBCYP11B1NPC1RAB9AMAOA | |
| SCHEMBL13695996 | 0.75 | MAOB (0.50) | MAOBNPC1RAB9AMAOAKDM4E | |
| SCHEMBL13892585 | 0.73 | MAOB (0.49) | MAOBNPC1RAB9AMAOAKDM4E | |
| SCHEMBL17115265 | 0.73 | IDO1 (0.43) | ROCK2MAOBCYP11B1NPC1RAB9A | |
| SCHEMBL19789801 | 0.71 | MAOB (0.47) | MAOBNPC1RAB9AMAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183356-A1 | New Imaging Agents and Methods of Identifying Same | THR TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170183356-A1 | New Imaging Agents and Methods of Identifying Same | THR TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-06-29 | — | — | US | disclosed |
| WO-2015143349-A1 | NEW IMAGING AGENTS AND METHODS OF IDENTIFYING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183356-A1 | New Imaging Agents and Methods of Identifying Same | DDX3X, DDX21, DAXX | ROCK2 277/4885MAOB 1522/4885CYP11B1 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.