Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL23531961 | 0.91 | ALDH1A1 (0.39) | ALDH1A1KDM4ETDP1ELANEGAA | |
| SCHEMBL910653 | 0.82 | NAPRT (0.41) | ALDH1A1GAAPOLBL3MBTL1CA4 | |
| SCHEMBL1370188 | 0.82 | MAPT (0.36) | ALDH1A1KDM4ETDP1GAATSHR | |
| SCHEMBL27175900 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4ETDP1ELANEGAA | |
| SCHEMBL56442 | 0.77 | ORAI1 (0.39) | ALDH1A1TDP1GAAPOLBRECQL | |
| SCHEMBL7040701 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAARECQLCA4 | |
| SCHEMBL1711735 | 0.75 | TGM2 (0.46) | ALDH1A1CA4CA6CA5ACA7 | |
| SCHEMBL28524847 | 0.74 | ELANE (0.44) | ALDH1A1KDM4ETDP1ELANEPOLB | |
| SCHEMBL20483698 | 0.74 | ALDH1A1 (0.52) | ALDH1A1GAAPOLBHSD17B10MAPT | |
| SCHEMBL1723147 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KDM4ETDP1ELANEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076533-A1 | SYNTHESIS OF LACTONE DERIVATIVES AND THEIR USE IN THE MODIFICATION OF PROTEINS | GENIE BIOTECH UK LTD. (GB) | 2022-10-26 | — | — | EP | claimed |
| CN-114085391-B | High-sensitivity flexible pressure sensing material in pure water and application thereof | 天津大学 | 2022-05-13 | — | — | CN | claimed |
| CN-114085391-A | High-sensitivity flexible pressure sensing material in pure water and application thereof | 天津大学 | 2022-02-25 | — | — | CN | claimed |
| US-10792620-B2 | Grafted ultra high molecular weight polyethylene microporous membranes | ENTEGRIS, INC. (US) | 2020-10-06 | — | — | US | claimed |
| EP-3390715-A1 | BORONIC ACID CONTAINING POLYMERS FOR PAPERMAKING PROCESS | Ecolab USA Inc. (US) | 2018-10-24 | — | — | EP | claimed |
| WO-2017106310-A1 | BORONIC ACID CONTAINING POLYMERS FOR PAPERMAKING PROCESS | ECOLAB USA INC. (US) | 2017-06-22 | — | — | WO | claimed |
| US-7988988-B2 | Contact lenses with mucin affinity | BAUSCH & LOMB INCORPORATED (US) | 2011-08-02 | — | — | US | claimed |
| EP-2344885-A2 | MATERIALS AND METHODS FOR RESOLVING POLYHYDRIC SPECIES BY ELECTROPHORESIS | The University of Bath (GB) | 2011-07-20 | — | — | EP | claimed |
| US-7832856-B2 | lens is coated with first polymer, such as a boronic acid-containing copolymer, having affinity to mucin, and second polymer which improves initial comfort of contact lens; during wear of lens, second polymer is removed from lens by blinking or tear fluids, and mucin complexes with first polymer | BAUSCH & LOMB INCORPORATED (US) | 2010-11-16 | — | — | US | claimed |
| WO-2010041037-A2 | MATERIALS AND METHODS FOR RESOLVING POLYHYDRIC SPECIES BY ELECTROPHORESIS | THE UNIVERSITY OF BATH (GB) | 2010-04-15 | — | — | WO | claimed |
| EP-1968658-A2 | CONTACT LENSES WITH MUCIN AFFINITY | BAUSCH & LOMB INCORPORATED (US) | 2008-09-17 | — | — | EP | claimed |
| WO-2008079495-A2 | COATINGS AND SOLUTIONS FOR CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 2008-07-03 | — | — | WO | claimed |
| US-20080151181-A1 | Coatings and Solutions for Contact Lenses | BAUSCH & LOMB INCORPORATED (US) | 2008-06-26 | — | — | US | claimed |
| US-20080151180-A1 | Coatings and Solutions for Contact Lenses | BAUSCH & LOMB INCORPORATED (US) | 2008-06-26 | — | — | US | claimed |
| WO-2007061919-A2 | CONTACT LENSES WITH MUCIN AFFINITY | BAUSCH & LOMB INCORPORATED (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116740-A1 | Contact lenses with mucin affinity | BAUSCH & LOMB INCORPORATED | 2007-05-24 | — | — | US | claimed |
| CN-120647981-A | Sericin low-hysteresis composite conductive hydrogel and preparation method and application thereof | 江南大学 | 2025-09-16 | — | — | CN | disclosed |
| US-20230212216-A1 | SYNTHESIS OF LACTONE DERIVATIVES AND THEIR USE IN THE MODIFICATION OF PROTEINS | GENIE BIOTECH UK LTD. (GB) | 2023-07-06 | — | — | US | disclosed |
| US-20040248326-A1 | Hydrogel compositions, devices, and microscale components | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-12-09 | — | — | US | disclosed |
| WO-2003051286-A2 | HYDROGEL COMPOSITIONS, DEVICES, AND MICROSCALE COMPONENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212216-A1 | SYNTHESIS OF LACTONE DERIVATIVES AND THEIR USE IN THE MODIFICATION OF PROTEINS | AGL, PGLS, DDOST | ALDH1A1 3862/4885KDM4E 1126/4885TDP1 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.