Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040697 | 0.84 | ALDH1A1 (0.42) | ALDH1A1RECQLSMN1; SMN2TSHRPLK1 | |
| SCHEMBL910653 | 0.81 | NAPRT (0.41) | ALDH1A1CA4CA6CA5ACA7 | |
| SCHEMBL56442 | 0.79 | ORAI1 (0.39) | ALDH1A1RECQLCA4CA6CA5A | |
| SCHEMBL4441444 | 0.77 | TRPV6 (0.44) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL20483698 | 0.76 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL1711927 | 0.76 | ALDH1A1 (0.45) | ALDH1A1RECQLSMN1; SMN2CA4CA6 | |
| SCHEMBL2243245 | 0.75 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2CA4CA6CA5A | |
| SCHEMBL28957792 | 0.74 | TGM2 (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14920515 | 0.74 | CETP (0.41) | ALDH1A1SMN1; SMN2TSHRGAAKDM4E | |
| SCHEMBL791334 | 0.74 | ALDH1A1 (0.42) | ALDH1A1RECQLSMN1; SMN2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | disclosed |
| EP-1259499-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060808-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |